5 août, par Sira A Franchi, Veronica Astro, Romina Macco, Diletta Tonoli, Jean-Vianney Barnier
Interneurons are essential modulators of brain activity and their abnormal maturation may lead to neural and intellectual disabilities. Here we show that cultures derived from murine medial ganglionic eminences (MGEs) produce virtually pure, polarized γ-aminobutyric acid (GABA)-ergic (...)
1er août, par Laura Pieri, Philippe Chafey, Morgane Le Gall, Guilhem Clary, Ronald Melki
BACKGROUND: α-Synuclein (α-Syn) fibrils are the main constituent of Lewy bodies and a neuropathological hallmark of Parkinson's disease (PD). The propagation of α-Syn assemblies from cell to cell suggests that they are involved in PD progression. We previously showed that α-Syn fibrils are toxic (...)
1er août, par Laura Pieri, Karine Madiona, Ronald Melki
The deposition of fibrillar alpha-synuclein (α-syn) within inclusions (Lewy bodies and Lewy neurites) in neurons and glial cells is a hallmark of synucleinopathies. α-syn populates a variety of assemblies ranging from prefibrillar oligomeric species to fibrils whose specific contribution to (...)
1er août, par Sumir Keenan, Nicolas Mathevon, Jeroen Mg Stevens, Jean Pascal Guéry, Klaus Zuberbühler
Long-term social recognition is vital for species with complex social networks, where familiar individuals can encounter one another after long periods of separation. For non-human primates who live in dense forest environments, visual access to one another is often limited, and recognition of (...)
An important diversity of animal species produces sounds during communication, orientation, movement, or prey-predator acts. These sounds are not distributed randomly in space and time and are therefore thought to follow assembly rules forming either acoustic populations or acoustic (...)
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