The Multidimensional Brain

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Sylvie Rétaux Team

Funding sources

Our work is currently supported by:
ANR-Blanc SVSE7, BLINDTEST project (2013-2016)
Equipe FRM (2015-2018)
Lidex Neuro-Saclay (2016)
Programme de collaboration Ecos-Nord Mexique (2016-2020) (...)

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Technical platforms

The DECA team is partner in the AMATRACE platform for the analysis of fish behavior, which is currently set up in Laure Bally-Cuif’s group (ZEN team of the Institute).
Our Astyanax fish facility (...)

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Publications

2016 Sylvie Rétaux, Alexandre Alié, Maryline Blin, Lucie Devos, Yannick Elipot, Hélène Hinaux (2016). Neural development and evolution in Astyanax mexicanus: comparing cavefish and surface fish (...)

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Teaching

Sylvie Rétaux gives lectures to Master Students (M1 and M2) for several Universities (Paris11-Orsay, Paris6, Paris7) on subjects related to Evolution, Development, Neurobiology.
Lucie Devos (...)

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Team members

List of the members of the Development & Evolution of the Forebrain team with Sylvie Rétaux as team leader.

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Development and Evolution of the Forebrain

The vertebrate forebrain has undergone an extraordinary diversification in the course of evolution. For instance, could anyone see that the mammalian cerebral cortex, with its well-known organization into 6 layers, and the so-called everted pallium of teleost fishes, are homologous brain regions? Using an evolutionary developmental approach, we aim to understand the molecular and cellular mechanisms which govern the unity (homology) and the differences (diversification) present in the forebrains of various vertebrates.
To this end, we use an original animal model: the blind cavefish Astyanax mexicanus, which we consider as a “natural mutant”. During its adaptation to life in total and permanent darkness, this fish lost its eyes (and its pigmentation).

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