The Multidimensional Brain
The Paris-Saclay Institute of Neuroscience (Neuro-PSI) is dedicated to basic Neuroscience, at all scales of analysis, from molecule to cognition and from embryo to adult. It is a joint Research Unit of the CNRS and Paris-Sud University (UMR9197), currently located in Gif-sur-Yvette and Orsay, 25km South to Paris. It forms, with its sister Institute NeuroSpin (CEA Saclay), the NeuroSaclay Center promoting Neuroscience at the highest international standards within the Paris-Saclay University.



A key point of learning theory demonstrated through optogenetics

The brain learns constantly to improve our actions according to our experiences. Several theories aim to account for this fundamental property, one of the most popular being reinforcement learning, also used in artificial intelligence. This theory postulates that learning emerges through a specific reinforcement of connections between neurons that are active during an event, an action, or a sequence of events and actions leading to a reward. One of the key points of this theory is that the more active involved neurons are, the faster and more solid the reinforcement of connection is. Thus the events that most strongly activate our brain should be learned in priority with respect to other events.


In order to demonstrate that this principle actually guides biological learning, the team of Brice Bathellier used two optical methods to read and modify the activity of large sets of genetically defined neurons (optogenetics).
The details of this study can be found in an article published in the journal Nature Communications in 2019, April 1st.


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Scientific conferences

Launching of the Neuro-PSI Talents Day

The Neuro-PSI Talents Day will take place Tuesday 4th June 2019 in salle de la Terrasse (Gif sur Yvette).
This day will be composed of 4 time plots (1 by department), each session will have :
- one presentation of 30 minutes by a guest researcher, belonging or not to NeuroPSI (20 minutes of presentation and 10 minutes of questions).
- 2 talks of 15 minutes by PhDs and/or post-docs.


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Scientific Themes

S. Creuzet Development-Evolution dept.

F. Rouyer Molecules-Circuits dept.

JM Édeline Cognition-Behavior dept.

P. Affaticati / A. Jenett Development-Evolution dept.

D. Shulz UNIC

A. Veyrac / S. Laroche Cognition-Behavior dept.

C. Huetz / JM Édeline Cognition-Behavior dept.

D. Vasiliauskas Molecules-Circuits dept.

M. Perron Development-Evolution dept.

S. Rétaux Development-Evolution dept.

J. Wu / G. Fortin Molecules-Circuits dept.

J. Fournier / Y. Frégnac ICN dept.


Available jobs

Thesis Projects in 2019

BioSigne and SDSV Thesis Projects

Post-doc position for spring 2019

New team : Neural Circuits & Behavior

M2 internships available

New team : Neural circuits & Behavior

POSTDOCTORAL position in Integrative Neuroscience

FRM Team : neural proceesing, neuromodulation and sensory plasticity


NeuroFrance 2019

Proposals for the next meeting in Marseille, 2019 May 22-24.

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