Le cerveau multidimensionnel

Accueil du site Neuro-PSI > Platforms > Neuro-PSI Platforms


The TEFOR infrastructure supports research on two alternative model species :
zebrafish and drosophila.
TEFOR is a distributed infrastructure composed of eleven partners. It is funded by a “Grand Emprunt Investissements d’Avenir” ANR grant.
We are looking for research program collaborators on genome editing in three species rat (TRANSGENESIS NANTES), zebrafish (AMAGEN) and drosophila (FLY ACILITY).


The major aims of the TEFOR infrastructure are :
- to provide transgenesis, mutagenesis, and phenotyping services and collaborative research projects in drosophila and zebrafish.
- to generate in both species new collections of transgenic lines.
- to develop technology projects in the areas of genome rewriting, viewing of 3D images and database archiving.


TALE-nuclesases (Transcription Activator Like Effector nucleases) and Cas9 endonucleases are at the basis of novel strategies for genome editing. They have been shown to work in a wide variety of model and non model organisms.


Recent publications :


High-resolution 3D imaging of whole organ after clearing : taking a new look at the zebrafish testis.
Frétaud M, Rivière L, De Job É, Gay S, Lareyre JJ, Joly JS, Affaticati P, Thermes V
Sci Rep. 2017 Feb 17 ;7:43012. PMID : 26923600

Altmetric it !


Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes.
Passoni G, Langevin C, Palha N, Mounce BC, Briolat V, Affaticati P, De Job E, Joly JS, Vignuzzi M, Saleh MC, Herbomel P, Boudinot P, Levraud JP
Dis Model Mech. 2017 Jul 1 ;10(7):847-857. PMID : 28483796

Altmetric it !


- TEFOR Core Facility









Elodie Dejob & Pierre Affaticati

  Webmaster Plan du site Planning Crédits
Syndication RSS  
  Format Mobiles
  Dev-Evo Cog-Comp Mol-Circ